Coexistence of adenosine deaminase, histidine decarboxylase, and glutamate decarboxylase in hypothalamic neurons of the rat
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منابع مشابه
Coexistence of adenosine deaminase, histidine decarboxylase, and glutamate decarboxylase in hypothalamic neurons of the rat.
Neurons immunoreactive for the enzyme adenosine deaminase (ADA) in the posterior basal hypothalamus of the rat have a distribution pattern similar to those immunoreactive for histidine decarboxylase (HDC) and are particularly numerous in the tuberal (TM), caudal (CM) and postmammillary caudal (PCM) hypothalamic magnocellular nuclei which harbor neurons containing glutamic acid decarboxylase (GA...
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Mammalian histidine decarboxylases have not been characterized well owing to their low amounts in tissues and instability. We describe here the first spectroscopic characterization of a mammalian histidine decarboxylase, i.e. a recombinant version of the rat enzyme purified from transformed Escherichia coli cultures, with similar kinetic constants to those reported for mammalian histidine decar...
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The role of histamine (HA) as a neurotransmitter in the CNS, although proposed a decade ago (Schwartz, 1975), has been only progressively recognized (reviewed by Schwartz et al., 1980, 1982, 1984; Hough and Green, 1984). One of the key pieces of expenmental evidence has been the demonstration that synthesis of the amine in CNS depends on a specific enzyme, L-histidine decarboxylase (HDC) (Schwa...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1985
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.05-12-03393.1985